Cushing’s Syndrome

Cushing’s syndrome (Canine Cushing’s Syndrome – Hyperadrenocorticism) is a hormonal disorder caused by the excess production of the hormone cortisol by the adrenal gland. Cortisol is a vital hormone that helps the body cope with stress and regulate many functions, but when it is secreted in excess, it may cause metabolic changes and damage to tissues and organs. This syndrome is common mainly in older dogs, especially of small and medium breeds such as Poodle and Schnauzer.

Symptoms and Diagnosis

The symptoms of Cushing's syndrome include excessive drinking (polydipsia), excessive urination (polyuria), increased appetite, obesity in the abdominal area, hair loss, thin skin and vulnerability to skin infections. In addition, dogs may show fatigue and intolerance to physical activity. The syndrome is diagnosed through special blood tests, urine tests and imaging tests such as ultrasound or CT to identify possible tumors in the adrenal gland or the pituitary.

Possible Complications

Without treatment, Cushing's syndrome may lead to severe complications such as diabetes, high blood pressure, chronic inflammations, tears in muscles and tendons and kidney failure. In addition, there is an increased risk of developing tumors in the adrenal gland.

Treatment

The treatment of Cushing's syndrome depends on the cause of the disease. If the syndrome is caused by a tumor in the pituitary, medication therapy will be given to reduce cortisol production, such as Trilostane (Vetoryl). In the case of a tumor in the adrenal gland, surgery to remove the tumor may be required. In certain cases, supportive treatment to improve the dog's quality of life will be recommended, including a balanced diet and ongoing veterinary follow-up.

Prevention

There is no definitive way to prevent Cushing's syndrome, but routine medical follow-up and periodic examinations for older dogs can help with early diagnosis of the disease. It is important to maintain a balanced diet and to prevent obesity, since obesity may worsen the symptoms of the disease.

Cushing’s syndrome is a chronic hormonal disease that may significantly affect the dog’s quality of life. Early diagnosis, appropriate treatment and close veterinary follow-up can improve quality of life and reduce the risk of severe complications. Dog owners should be aware of the symptoms and consult a veterinarian in the event of a suspicion of the disease.